TRM: Pituitary Progenitor Cell Line (alpha T1-1)

Technology Description

A mammalian cell line immortalized at a specific stage of development. Targeted oncogenesis using a fragment of the LH- alpha promoter linked to T-antigen resulted in this progenitor cell which expresses only the a-subunit of the human gene. This cell line represents a more primitive or less differentiated state of pituitary development. (reference)